Human cell

Primary Spermatocytes (DNA Shufflers)

Primary spermatocytes are the second step on the path to sperm. They do something amazing: they shuffle their DNA.

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Lesson 1

A big, busy cell

When a spermatogonium splits, some new cells grow into primary spermatocytes. They sit a little farther in from the wall of the tiny tubes in the testes.

They are large, round cells. Their big nucleus is full of DNA, bundled into threads called chromosomes.

Wow!

This DNA shuffling is part of why brothers and sisters don't look exactly alike, unless they're identical twins!

Watch and learn

Meiosis (UPDATED 2026)

By Amoeba Sisters. Good for older kids.

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